郑州大学生物工程系研究生导师——郑鹏远

郑大考研网1

特聘教授，博士。新加坡国立大学博士，加拿大多伦多大学博士后，美国胃肠病学会、微生物学会及加拿大胃肠病学会会员，河南抗癌协会委员,省消化学会委员，省微生物学会病毒学分会委员兼秘书。
Journal of Canadian Gastroenterology 杂志审稿人
  
著作：
    郑鹏远. LAK 细胞治疗乙型肝炎. 张建营 郑鹏远 张毅(主编): 病毒性肝炎 研究与实践.
    中国科学技术出版社. 1996.
获奖：
     加拿大胃肠病学---加拿大医学科学院 (Canadian Institute of Health Research (CIHR) 研究奖 2002
     加 拿大胃肠病学---加 拿大医学科学院研究奖 2001
发表文章：
1. Zheng PY, Jones N.L. Helicobacter pylori strains expressing vacuolating cytotoxin interrupt phagosome maturation in macrophages by recruiting and retaining TACO (coronin 1) protein Cellular Microbiology 2003; 5(1):25-41.
2. Zheng PY, Hua J. Lim KG, Ho B. Non interference of Lewis B expression in H. pylori with the bacterial adhesion property. World J. Gastroenterology 2003; 9(1):122-124
3. Zheng PY, J.Hua, K.G. Yeoh and B. Ho. Association of peptic ulcer with increased expression of Lewis antigens but not cagA, iceA and vacA in Helicobacter pylori isolates in an Asian population. Gut 2000;47(1):18-22.
4. Zheng PY, NL Jones. Recent advances in Helicobacter pylori infection in children: from the petri dish to the playground. Canadian J. Gastroenterology 2003 17(7):448-454.
5. Zheng PY, J. Hua, H.C. Ng and B. Ho. Unchanged characteristics of Helicobacter pylori during its morphological conversion. Microbios 1999;98:51-64.
6. Monteiro MA, Zheng PY, Bow Ho2, Shin-ichi Yokota3, Ken-ichi Amano3, Zhi-jun Pan4, Douglas E. Berg4, and Kenneth H. Chan1, Leann L. MacLean1 and Malcolm B. Perry1. Expression of histo-blood group antigens by lipopolysaccharides of Helicobacter pylori strains from Asian hosts: the propensity to express type 1 blood-group antigens. Glycobiology 2000;10:701-713.
7. Hua J, Zheng PY, K.G. Yeoh and Ho Bow. The status of the cagA gene does not predict Helicobacter pylori-associated peptic ulcer disease in Singapore.
Microbios. 2000;102(402):113-20.
8. Hua J, Zheng PY and Ho Bow. Species differentiation and identification in the genus of Helicobacter. World J. Gastroenterology 1999;5:7-9.
9. Monteiro MA, Zheng PY, Appelmelk BJ, Perry MB. The lipopolysaccharide of Helicobacter mustelae type strain ATCC 43772 expresses the monofucosyl A type 1histo-blood group epitope. FEMS Microbiol Lett 1997;154:103-109.
10. Hua J, Zheng PY, Teo Keng Fong, Khin Mar Mar and Ho Bow. Helicobacter pylori acquisition of metronidazole resistance by natural transformation in vitro. World J. Gastroenterology 1998;4:385-387.
11. Appelmelk BJ, Martin SL, Monteiro MA, Clayton CA, McColm AA, Zheng PY, Verboom T, Maaskant JJ, van den Eijnden DH, Hokke CH, Perry MB, Vandenbroucke-Grauls CM, Kusters JG. Phase variation in Helicobacter pylori lipopolysaccharide due to changes in the lengths of poly(C) tracts in alpha3-fucosyltransferase genes. Infect Immun 1999;5361-5366.
12. Hua J, Bow Ho, Zheng PY, KG Yeoh. Prevalence of primary Helicobacter pylori resistance to metronidazole and clarithromycin in Singapore. World J Gastroenterol. 2000 Feb;6(1):119-121.
13. Hua J, KG Yeoh, Zheng PY, Han Chong Ng, and Bow Ho. Susceptibility testing of Helicobacter pylori to metronidazole and DNA fingerprinting of resistant strains in Singapore. J. Microbiol. Biotechnol. 1999;9:328-333.
14. Appelmelk BJ, Shiberu B, Trinks C, Tapsi N, Zheng PY, Verboom T, Maaskant J, Hokke, CH, Schiphorst WE, Blanchard D, Simoons-Smit IM, van den Eijnden DH,Vandenbroucke-Grauls CM. Phase variation in Helicobacter pylori lipopolysaccharide. Infect Immun 1998;66:70-76.
15. Monteiro MA, Chan KH, Rasko DA, Taylor DE, Zheng PY, Appelmelk BJ, Wirth HP, Yang M, Blaser MJ, Hynes SO, Moran AP, Perry MB. Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. Molecular mimicry between h. pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms. J Biol Chem 1998;273:11533-11543.
16. Hua J, Ho B, Zheng PY, Yeoh Khay-guan, Ng Han Chong, and Lim Seng Gee. Coexistence of Helicobacter pylori spiral and coccoid forms in experimental mice. World J. Gastroenterology 1998;4:485-488.
17. Hua J, Khin MM, Zheng PY, Yeoh Khay-guan, and Ho Bow. Serum IgG response to differentiated antigens of Helicobacter pylori. World J. Gastroenterology 1998;4:249-251.
18. Hua J, K.G. Yeoh, H.C. Ng, Zheng PY, S.G. Lim and B. Ho. Improving the success of culturing Helicobacter pylori from gastric biopsies. Microbios 1998;96:95-101.
19. 郑鹏远，唐芙爱，华杰松，段芳龄。幽门螺杆菌二型性的研究. 中华消化杂志1999;4:230-232.
20. 郑鹏远，唐芙爱，Appelmelk BJ, Verboom T，段芳龄. 幽门螺杆菌和雪貂螺杆菌表达血型抗原. 中华消化杂志 1999;2:85-86.
21. 郑鹏远, 何文林，段芳龄. 胃癌,消化性溃疡患者幽门螺杆菌和iceA基因的研究. 胃肠病学及肝病学杂志 1999;8:110-112.
22. 郑鹏远，王军，段芳龄。 人 LAK 细胞对 H7402 细胞的杀伤及形态学观察。. 中华消化杂志.1993;3:157-159.
23. 王军, 郑鹏远, 段芳龄,郑娟.　ＬＡＫ　细胞对小儿白血病细胞的杀伤作用的研究。中华血液病杂志1994
24. 郑鹏远，李文华，樊晓明，杨光，段芳龄. 盐酸，胆盐和尿素对幽门螺杆菌生存的研究。 中华消化杂志. 1990;6:320-322.
25. 郑鹏远，蒋笑平，樊晓明，杨光，段芳龄. 测量胃液中尿素含量诊断幽门螺杆菌感染。 中华消化杂志 1990;5:298-299.
26. 郑鹏远，樊晓明，杨光，段芳龄。 幽门螺杆菌的系列研究。. 胃肠病学及肝病学杂志 1993;1:55-58.
国际会议大会发言：
27. Zheng P.Y. and N.L. Jones. Vacuolating cytotoxin produced by type 1 Helicobacter pylori disrupts phagosome maturation and promotes bacterial survival in macrophages. Digestive Disease Weak (DDW) 2003, Orlando, Folorida, USA 美国。
28. Zheng P.Y. and N.L. Jones. Evade of host immune response by disruption of phagosome maturation by type I Helicobacter pylori strains. Gastroenterology Digestive Disease Weak (DDW),2002　 San Francisco, USA　美国。
29. Zheng P.Y., J. Hua, K.G. Yeoh, K.Y. Ho and B. Ho. Increased expression of Lewis antigens but not cagA, iceA, vacA, and babA2 in Helicobacter pylori from peptic ulcer patients in an Asian population. 2000 European Helicobacter pylori conference, Rome, Italy, 意大利。
摘要：
30. Zheng P.Y. and N.L. Jones. Vacuolating cytotoxin produced by type 1 Helicobacter pylori strains disrupts phagosome maturation and promotes bacterial survival in macrophages. Gastroenterology 2003
31. Zheng P.Y. and N.L. Jones. Evade of host immune response by disruption of phagosome maturation by type I Helicobacter pylori strains. Gastroenterology 2002
32. Zheng P.Y. and N.L. Jones. Inhibition of phagosome-lysosome fusion by type 1 Helicobacter pylori strain. Canadian Journal of Gastroenterology 2002;16 (Suppl):66A.
33. Zheng P.Y., J. Hua, K.G. Yeoh, K.Y. Ho and B. Ho. Increased expression of Lewis antigens but not cagA, iceA, vacA, and babA2 in Helicobacter pylori from peptic ulcer patients in an Asian population. Gut 2000;47(Suppl):A6 (Abst).
34. Zheng P.Y., H.C. Ng, J. Hua, and B. Ho. Lewisb expression in Helicobacter pylori does not interfere with the bacterial adhesion property in vitro. Gut 2000;47 (Suppl):A7 (Abst).
35. Zheng P.Y., Duan FL. Microecology of Campylobacter pylori. J of Gastroenterology and Hepatology.1989 (suppl).